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DIABETES

Brushing your teeth can also reduce your risk of diabetes, do you dare to perfunctory?

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How many times do you brush your teeth a day?Most people brush each morning and evening, but a recent study showed that brushing your teeth twice a day is not enough in some ways!Brushing your teeth 3 times a day can reduce your risk of diabetes, keep your mouth clean, freshen your breath, and prevent tooth decay, which is the purpose of most of us.However, the benefits of brushing your teeth are much more than that.Recently, a study published in the Journal of Diabetes indicated that brushing teeth more than or equal to 3 times a day can reduce the risk of diabetes.The results of the study show that brushing your teeth 3 or more times a day reduces the overall risk of diabetes by 8%.Among them, the impact on women under the age of 51 and women is more obvious.Perhaps the teeth also adhere to the principle of “three important things to do three times”. The study found that for people under the age of 51, brushing their teeth twice a day compared to people who brush their teeth once or not, the risk of diabetes is relatively reduced by 10%.However, for men and people over the age of 52, there is no significant difference in the risk of diabetes between brushing twice a day and brushing once a day, or even not brushing.Therefore, if conditions permit, brushing your teeth 3 times a day will make you profitable!How is tooth brushing related to diabetes?Brushing your teeth is the most basic measure to protect our oral health. It can remove food debris and some plaque in our mouth, and prevent problems such as periodontal disease, dental caries, and tooth decay.The researchers said that the poor oral environment may cause oral bacteria to enter the bloodstream, causing transient infection and systemic inflammation, and the inflammation itself is related to the occurrence and development of insulin resistance and diabetes.In fact, more than dental health problems can affect the risk of diabetes. Having diabetes can also increase the risk of oral diseases.Related studies have shown that the risk of periodontitis in patients with diabetes is three times that of patients without diabetes.The control of blood sugar can delay the progress of periodontal disease.Therefore, whether you have diabetes or not, brushing your teeth is a must!The original content of 39Health.com (www.39.net) may not be reproduced without authorization, and offenders will be investigated.For content cooperation, please contact: 0000 or 0000

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DIABETES

UZI has retired, how much harm will type 2 diabetes cause to people?

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Uzi (Jane proud) retired, and many people’s youth is over.Before the 2020 LPL summer game RNG team roster was released, when uzi did not appear on the list, many netizens made various guesses.And this afternoon, Uzi posted on Weibo, “It’s a pity to tell everyone that I’m proud to decide to retire.” In this Weibo, Uzi mentioned that because of stress, obesity, irregular diet, staying up late, etc.He checked out type 2 diabetes during a physical examination last year, and the conversational hemoglobin index reached 11%.Although he began to change his way of life, but because of taking medicine, his mental state was not as good as before, and he even had the risk of complications.Uzi said that due to the fact that the original hand injury was more serious, his physical conditions have not allowed him to continue fighting.Diabetes in adolescents is not alone. Poor lifestyle may ruin you!Uzi, born in 1997, is only 23 years old this year, but has been diagnosed with type 2 diabetes.When Uzi retired, the type 2 diabetes he mentioned also followed the hot search.People who need to focus on preventing type 2 diabetes, in addition to the middle-aged and elderly people whose body functions are not as good as before, there are young people with unhealthy lifestyles.Genetic factors are one of the main causes of diabetes in adolescents. In addition, a large proportion of adolescents with diabetes can be attributed to poor lifestyle and obesity.Obesity is an important risk factor for the onset of type 2 diabetes in young people. Regular consumption of unhealthy eating habits such as sweets and carbonated drinks further increases the risk of disease; while a sedentary lifestyle increases the risk of obesity, it also affects the incidence of type 2 diabetes.As mentioned in the blog post announced by Uzi’s retired officer: “Perennial stress, obesity, irregular diet, staying up late”, etc., will cause abnormal endocrine levels, increase the risk of insulin resistance, and then trigger type 2 diabetes.What happens if you let it go?Uzi’s retired official blog post has another keyword: “Complications.”When young people suffer from type 2 diabetes, they often do not pay as much attention as the middle-aged and elderly people.In fact, in the face of illness, everyone is “equal”.If blood sugar is not well controlled, let it continue to develop, the following complications may occur.1. Diabetic foot This is one of the more common complications of diabetic patients. Patients will have peripheral nerve and microvascular lesions, and the patient’s pain nerves will be damaged as a result.In this way, the sensitivity of the patient’s feet to external stimuli and injuries will be much reduced, and even some feet will be unconscious directly, and it is easy to get burned by heating in winter.2. Diabetic nephropathy, also known as glomerulosclerosis, is a very common complication that occurs in diabetic patients.And this complication is difficult to treat. It is a microvascular complication that can cause kidney damage in patients.Urine protein, pyelonephritis, etc., which continue to develop will threaten the life of the patient.3. The risk of atherosclerosis in patients with cardiovascular disease and diabetes will be much higher than that in normal people. It occurs in patients with type 2 diabetes.Coronary heart disease, cardiomyopathy, etc. mainly occur, and patients suffer from palpitation and chest pain.4. Diabetic eye disease due to long-term changes in blood sugar levels will cause damage to the fundus retinal small blood vessels. This damage will cause severe vision loss. It is reported in the literature that 1/3 of diabetic patients will develop diabetic retinopathy and diabetic macular edemaDME) is one of the most common and serious complications of diabetic retinopathy.The original content of 39Health.com (www.39.net) may not be reproduced without authorization, and offenders will be investigated.For content cooperation, please contact: 0000 or 0000

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Exercise can help control sugar, and diabetes patients are also taboo?

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Everyone knows that in addition to controlling diet, exercise is also a good way to lower blood sugar because exercise can consume excess calories in the body, thereby reducing blood sugar levels.So, how can sugar friends exercise to really lower blood sugar?For diabetics, you can choose moderate-intensity aerobic exercise, such as walking, medium-speed walking, jogging, jumping aerobics, tai chi, cycling, etc. These non-vigorous exercises are more suitable for sugar friendsof.Among many sports, walking is the safest and easy to stick to, which is more suitable for the elderly.Keep no less than 150 minutes a week, and at least 30 minutes of exercise each time can achieve a better sugar control effect.For healthy people, there is no contraindication in choosing exercise time, but for diabetic patients, you need to pay attention.The blood sugar of a diabetic patient is very unstable, and when the patient is exercising, the body consumes energy, thereby affecting the blood sugar, causing the blood sugar to fluctuate.Therefore, it is more suitable for such patients to exercise one hour after a meal, and it can also avoid hypoglycemia coma caused by not eating in time and exercising too much.When exercising, there are still some sports taboos that you need to pay attention to, such as: 1. Avoid morning exercises. Many people will feel that the morning air is relatively fresh, and people will also have a good mood. Morning exercises are better, why should they be taboo?What?It should be known that although the air is better in the morning, the temperature is relatively low, and the sympathetic nerves of the human body are relatively easy to be excited. Under the stimulation of cold air, it is easy to induce other diseases.In addition, many people exercise in the morning on an empty stomach, which can easily cause hypoglycemia and even coma. Therefore, it is not suitable to exercise in the morning.2. Avoid violent training. Many diabetic patients want to quickly consume excess sugar in the body through a lot of exercise.However, high-intensity exercise also has higher requirements on the body. Excessive exercise will not only benefit, but it may cause hypoglycemia in severe cases. When the blood sugar level in the body fluctuates up and down, it isThere is no benefit.3. Avoid taking the stone road. The nerves of diabetic patients are less sensitive and insensitive to external stimuli. In many cases, they are not aware of the injury, so for patients, they need to protect themselves, especially their feet.If accompanied by pathological changes of the lower extremity blood vessels, the wound healing ability will be reduced, and the wound will continue to be infected and ulcerated.So for diabetics, it is better to take a smoother path.Remember not to go to the meridian with bare feet to pass through the meridians, as this can easily hurt your feet.

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DIABETES

Fecal transplantation may treat obesity and type 2 diabetes, and the potential for medical value of microbial treasures is huge

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It is understood that obesity and type 2 diabetes are related to the imbalance of intestinal flora.Recent studies have found that fecal transplantation can help fight obesity and type 2 diabetes!This new discovery was published in the top journal Gut, which attracted industry attention.The research results were explored and released by researchers at the University of Copenhagen.They extracted the feces of mice eating a standard low-fat diet, filtered out concentrated phages, and transplanted them into mice that maintained a high-fat diet, and then continued to give mice a high-fat diet.During the observation, it was found that after receiving the transplanted virus, the obese mice significantly lost weight and the risk of type 2 diabetes was reduced.The first author of the study, Dr. Rasmussen, said: “This method of fecal transplantation changes the composition of the intestinal microbes so that mice with unhealthy lifestyles will not cause some common diseases due to poor diet.”In addition to discovering that the composition of viruses (bacteriophages) in the gut plays a crucial role in this microbiome balance, the method of filtering and concentrating the target microorganisms also solves a major problem in fecal transplantation-unfiltered fecesTransplantation can spread disease unintentionally.Last year, NEJM reported that an American patient died from this condition, which was also the world ’s first death due to fecal transplantation.The accident occurred in Massachusetts General Hospital.A 73-year-old man received fecal transplant oral capsules (NCT03720392) and experienced fever (39.7 ° C), chills, and changes in mental state after the trial medication, and eventually died of severe sepsis.The blood culture results showed that he was infected with a rare Escherichia coli (ESBL-producing E. coli) and originated from fecal transplant material.The paper pointed out that there are 21 other people who also took transplant capsules derived from the same donor. Only one of them had serious side effects. The remaining people tested positive for bacteria, but did not show symptoms.The adverse reactions of fecal transplantation include bacterial blood infection, fever, SIRS-like syndrome, aggravating the condition of patients with inflammatory bowel disease, and mild intestinal discomfort, but this discomfort generally disappears quickly after surgery, including bleeding, Diarrhea, bloating, abdominal pain, constipation, cramps and nausea.Since the outbreak of New Coronary Pneumonia, it has been confirmed that the virus will spread through the fecal mouth, which has also caused new fecal transplant-related concerns.Therefore, the guidelines and consensus emphasize the importance of standardized management of fecal transplantation, including material preparation, donor screening, and fecal transplantation operation specifications.After the above deaths, the US FDA also emphasized that fecal transplantation is still in the research stage, and donor selection should be strictly controlled.The guidelines and consensus stipulate that when selecting donors, close relatives are usually selected, but in the case of C. difficile treatment, family members and close contacts may be more likely to be carriers, so screening donor medical history, such as chronic diseases (such as intestinalIrritability, Crohn’s disease, gastrointestinal cancer, etc.), as well as examination of gastrointestinal pathogen infections (such as cytomegalovirus, salmonella, gastrointestinal parasites, etc.) are necessary.Obesity and smoking are also excluded.Sample preparation has not yet reached consensus on laboratory standards, and the recommended fecal material size is 30 to 100 grams.And fresh feces with strong bacterial viability should be collected and samples should be prepared within 6-8 hours.The sample is then diluted 2.5–5 times with saline, sterile water, or 4% milk.The suspension is then filtered through a filter and transferred to a drug delivery container and administered in a clinical environment.The concept of using feces to treat colon diseases originated in India.In some ancient Indian documents dating back more than 3,000 years, recommendations for treating various digestive tract diseases through the intake of cow dung and cow urine are documented.As early as the Eastern Jin Dynasty in the 4th century AD, the ancient Chinese medical book “Elbow Reserve Urgent Formula” also recorded the method of using fecal juice to treat food poisoning and severe diarrhea; in the 16th century after 1200, Li Shizhen in the Ming Dynasty in the “Compendium of Materia Medica”It also pointed out that the use of “yellow soup” (also known as “golden syrup”) containing fresh, dried or fermented feces can treat severe diarrhea, fever, vomiting and constipation.The first use of fecal transplantation in Western medicine was in 1958. American physician Ben Eiseman and his colleagues used fecal enema to treat four patients with C. difficile critical illness and quickly returned them to health.In recent years, fecal transplantation has become a popular method for treating severe diarrhea caused by C. difficile infection.Its efficacy in treating other gastrointestinal diseases including colitis (which may be more effective than vancomycin), constipation, irritable bowel syndrome, and neurological diseases such as multiple sclerosis and Parkinson’s disease has been experimentally confirmed.Research on fecal transplantation also involves the field of oncology, used to prevent or treat post-transplantation complications, and to improve the efficacy of immunotherapy.In 2012, the Massachusetts Institute of Technology established the first public fecal bank, and now there are many fecal banks throughout Europe to meet the growing demand for testing and treatment.The hypothesis behind the mechanism of fecal transplantation includes the use of competitive ecological footprints of beneficial flora in feces, colonization resistance, biological oxygen deprivation, immune regulation, lowering of intestinal pH and nutrition of bacterial metabolites.Microorganisms that inhabit the intestines all year round in transplanted feces, intestinal epithelial cells and other biological components and food-borne abiotic components (undigested food) and secretions from the stomach, intestine, pancreas and liver (such as hormones,Enzymes, mucus, bile salts, etc.) together constitute the intestinal micro-ecosystem.The significance of fecal transplantation lies in the reconstruction of intestinal microecological structure..
The phage colonization research of the University of Copenhagen shown above is an important research field of fecal transplantation.Phage colonization can work quickly and with good safety.Although the mouse experiment is only the first step, the widespread use of fecal transplantation still needs many years of animal and human test evidence.But in the long run, a well-defined phage mixture that minimizes side effects may be developed in the future to treat a variety of diseases.The current problem of antibiotic resistance is becoming more and more serious, and the testing and research of hundreds of millions of microorganisms in stool may become more and more important. After avoiding the risks associated with transplantation, the future of stool transplantation applications will be very worth looking forward to.The above content is only authorized for exclusive use by 39Health.com, please do not reprint without the authorization of the copyright party.

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DIABETES

Attention diabetic patients!

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Once you have diabetes, you have to control your blood sugar for a long time, which makes many patients wonder: Why do you have to take medicine to control your blood sugar?Because the most terrible thing about diabetes is that long-term high blood sugar leads to a worsening of the condition, which leads to a series of complications. The most headache is diabetic nephropathy.What is the performance of a kidney problem in diabetic patients?The kidney is one of the more important metabolic organs in the human body.Once the kidneys have problems, the metabolism of the whole body will fail, and a series of uncomfortable symptoms such as increased blood pressure and calf cramps will appear.1. In general, blood sugar is out of control. Diabetics should always control their blood sugar to prevent complications caused by increased blood sugar.But when a diabetic suffers from uncontrollable blood sugar, it is likely that diabetic nephropathy is at play.When kidney function declines, there will be abnormalities in filtering sugar, resulting in increased blood sugar.Once the blood sugar cannot be well controlled for a long time, it will accelerate the development of diabetic nephropathy.At this time, it is best to seek medical treatment in time.2. Sudden rise in blood pressure Most people with diabetes are usually accompanied by high blood pressure, but as long as the patient pays attention to diet, they can control high blood pressure.If a diabetic patient has a sudden increase in blood pressure under normal blood pressure, it must be considered whether it is related to diabetic nephropathy.Because the decline in kidney function will cause sodium in the body to be excreted in a timely manner, causing a sudden increase in blood pressure.3. Frequent calf cramps For patients with diabetic nephropathy, calf cramps are one of the more common symptoms.This is mainly because a decrease in kidney function reduces hormones that regulate calcium metabolism, which hinders calcium absorption, which makes patients prone to osteoporosis and other problems, such as calf cramps.4. Body edema The kidneys regulate most of the body’s water, but diabetic patients suddenly have symptoms of body edema, such as edema symptoms on the face, ankles and lower limbs. At this time, it is likely that diabetic nephropathy is in trouble.In addition, if the patient has severe diabetic nephropathy, proteinuria is likely to occur.At first, the protein in urine is relatively small, and when the amount of proteinuria in urine is increasing, it indicates that patients are likely to develop renal failure and uremia, which is the most serious consequence of diabetic nephropathy.How do diabetics prevent complications of kidney disease?1 Control blood pressure Diabetics should control their blood pressure and try to keep the blood pressure in a stable state.Because when the diabetic patient does not control the blood pressure and the blood pressure rises and cannot fall for a long time, it is very likely to cause diabetic nephropathy.Therefore, to prevent diabetic nephropathy, controlling blood pressure is critical.Diabetics should choose their own antihypertensive drugs under the guidance of doctors, so as to better stabilize blood pressure and protect the kidneys, preventing the occurrence of diabetic nephropathy.2 Control protein intake When diabetic patients want to maintain kidney health, they must control protein intake.In addition, human life activities are also inseparable from protein, so diabetics should try to choose some high-quality protein, such as usually can eat some lean meat, milk, eggs and so on.3 Pay attention to the blood lipid level. When the patient’s blood lipid concentration is too high, it will lead to the disorder of fat metabolism, which will cause abnormal renal function.Therefore, patients usually have to control the cholesterol and triglyceride values.In daily life, it is best to quit smoking and alcohol, exercise properly, and maintain a positive and optimistic attitude.This can better prevent the occurrence of diabetic nephropathy.When there are abnormalities in the body, it is best not to delay, and go to the hospital for examination in time is the correct way.

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DIABETES

As soon as the blood sugar is high, six symptoms follow, pay attention!

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According to data, the number of patients with diabetes in China reached 114 million in 2017, and it is expected to reach about 150 million by 2045.Faced with such a high incidence, we all need to be alert to the invasion of diabetes.So what are the precursors to diabetes?How can we stabilize blood sugar?6 symptoms often appear when blood sugar rises!1. It is easy to be hungry. The increased sugar in the body of diabetic patients will be excreted as urine sugar, and the calories needed by the body will not be satisfied.Because of this, I eat more, even by eating more sweets.Therefore, once a similar situation occurs, you need to be vigilant and go to the hospital for examination to rule out diabetes.2. Body weight loss Many diabetic patients will appear unexplained thin.Although the appetite is good, the weight goes down quickly.3. I always feel thirsty and always feel dry mouth, thirst, a lot of drinking water can not be relieved, increased urination, which is also the pre-symptoms of many diabetic patients.4. Patients who often feel tired and lethargic diabetes often feel fatigued, mentally unconscious, drowsy, and sore and weak.These conditions occur because high blood sugar can lead to yin deficiency, which should be paid attention to.5. Some people with diabetes with numbness or trembling may also experience numbness or trembling, and some may also feel tingling fingers.6. Patients with eye fatigue or blurry diabetes Some eyes may also experience uncomfortable symptoms, such as dry eyes, fatigue, and blurred vision.If diabetics can find their condition early and can stabilize their blood sugar, they must be able to stabilize the condition and avoid causing more damage to the body caused by complications later on.In our daily life, we need to control our diet reasonably, maintain regular exercise, control oil and salt, and quit smoking and alcohol. Only then can we help control blood sugar at a normal level, and prevent diabetes from further developing, causing serious complications.

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Why do people with diabetes have low immunity and are easily infected?

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Ordinary people bite a few mosquitoes. At most, they bleed out a bit of blood, pack a bag, and apply a little bit of fengyoujing, which fades the next day.As a seven-year veteran “old sugar friend”, Aunt Zhang was bitten by a mosquito on her left leg, which caused serious consequences after being slapped with a palm.When the aunt took a bath the next day, she found that the area where the mosquito had bitten became inflamed, her legs started to swell and her skin ruptured, and there were purulent discharges, and she had to go to the hospital.The doctor who received the consultation analyzed that first, the current mosquitoes were too poisonous, and second, that Aunt Zhang’s immunity was too weak.Studies have shown that people with diabetes have impaired immune function and are susceptible to infection. Diabetes is the enemy of human health, and the number of diseases worldwide is rising.The number of diabetics in China is the highest in the world, exceeding 200 million.In recent years, there have been many studies on the immunity of diabetics.Among them, experts from the Toronto General Hospital Research Institute in Canada found that patients with type 2 diabetes or obesity at high risk of diabetes have much lower immune responses to infections and pathogens than healthy people.A study published in the international academic journal “Journal of Diabetes Investigation” showed that chronic inflammation in patients with type 2 diabetes may be related to impaired immune function, so they are more likely to be infected.In this New Coronary Pneumonia epidemic, diabetics have become the targets of the New Corona Virus attack due to low immunity. Therefore, in the face of no vaccines and no special drugs, sugar friends can only protect themselves and improve their immunity.Why do diabetics suffer from low immunity?During the National Nutrition Week, Zhao Yongyi, director and deputy chief physician of the Department of Clinical Nutrition of the First Affiliated Hospital of Guangdong Pharmaceutical University, gave an online popular science lecture entitled “Reasonable Diet, Improving the Immunity of ‘Sugar'”.She said that the most important reason for the low immunity of diabetic patients is the disease itself.Diabetes is caused by metabolic disorders due to absolute or relative lack of insulin.The so-called absolute deficiency is insufficient insulin secretion; and the relative deficiency is that a lot of insulin is enough, but it is not used.”In addition to poor glucose metabolism, insulin also promotes the synthesis of protein and fat, so lack of insulin will inevitably lead to obstacles in the synthesis of protein and fat.” Zhao Yongyi said, in addition, insufficient insulin will cause cell hunger, this feeling of hunger encourages the bodySince starting other channels to decompose some nutrients into energy that the body can use.As a result, the synthesis is reduced, but the decomposition is increased, which in turn causes a shortage of body-producing nutrients (including carbohydrates, proteins, fats).In short, it is precisely the primary disease that is not well controlled, the disorder of insulin metabolism, which leads to a series of metabolic disorders and a lack of a series of substances in the body, including many immune-related nutrient deficiencies.The second important cause of immunodeficiency is the unreasonable diet of diabetics.”This kind of patients are often encountered in outpatient clinics and go to two extremes,” Zhao Yongyi said. The extreme is that patients clearly know that high blood sugar is harmful, but they can’t control their mouths.It is important to know that the damage to islets caused by overeating is irreversible. Uncontrolled diet will increase the disturbance of nutrient metabolism, and many immune-related nutrients will be lacking.The second extreme is excessive fear of diabetes. Without consulting a specialist or nutritionist, he over-died on his own and over-abstained, resulting in insufficient intake of nutrients such as protein, vitamins, and trace elements.In addition, factors such as genetics, age, decreased exercise capacity, high stress, poor sleep quality, and poor mood can also affect the immune system of diabetics.Sugar friends should have a reasonable diet and supplement 8 major nutrients to improve immunity. In the “five carriage principles” for the treatment of diabetes, the leading horse is nutrition therapy.Zhao Yongyi emphasized that diabetics should abide by scientific diet principles, including avoiding obesity, regular meals at three meals, balanced and reasonable food, healthy cooking methods, more cooking and less frying, light and less salt, frequent consumption of high-fiber foods, pay attention to choose GI relativeLower food.(Picture from doctor PPT) In terms of improving immunity, diabetic patients appropriately increase the intake of the following nutrients: 1. Protein: protein is the composition of tissues and cells of the whole body. Ingestion of protein is conducive to stimulating islet B cells to release insulin, which is beneficialControl postprandial blood sugar.Meat, fish, eggs, milk, soybeans and products are all foods rich in high-quality protein.2. Vitamin A: Known as the “guardian” of the first defense line of immunity, it can improve the stability of the cell membrane and maintain the integrity of the mucosal barrier.It is recommended to eat more animal liver, egg yolk, milk powder, carrots (carotene can be converted to vitamin A in the body), red yellow and dark green vegetables, fruits.3. Vitamin B: assists the normal operation of the immune system.Vitamin B1 and B6 are rich in meat, vegetables, grains, and beans. B2 is more in liver, kidney, eggs, and milk of animals. The vast majority of B12 comes from meat.4. Vitamin C: helps immune defense, like fresh vegetables and fruits are rich sources of vitamin C.5. Vitamin E: It is an important antioxidant.Edible oil is its main source, in addition, beans, nuts and vegetables also contain a certain amount of vitamin E.6. Iron: Iron deficiency will affect the cell-mediated immune function and reduce the ability to resist infection.Red meat, animal blood, animal internal organs, etc. are rich in heme iron, suitable for consumption..

7. Calcium: closely related to the human immune system, milk and milk products are the best source of calcium, and soybeans and soy products also contain more calcium.8. Zinc: It is essential for the normal development and function of cells that mediate innate and adaptive immunity.Shellfish, red meat, animal offal, dried fruit, cereal germ, and wheat bran contain more zinc.(Correspondent Wang Yuan) The original content of 39Health.com (www.39.net) shall not be reproduced without authorization, and offenders will be investigated.For content cooperation, please contact: 0000 or 0000

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DIABETES

A study of 140,000 people found that drinking more whole milk can actually reduce the risk of hypertension and diabetes

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Metabolic syndrome (MetS) is characterized by the appearance of 5 common metabolic abnormalities, which can be diagnosed at 3/5 of the following conditions: 1) Blood glucose> 100 mg / dl; 2) Waist circumference male ≥2550px female ≥2200px; 3) Triglyceride ≥150mg / dl; 4) High-density lipoprotein cholesterol (HDL-C) <40mg / dl; 5) Blood pressure ≥130 / 85mmHg or taking antihypertensive drugs [1].MetS is associated with increased mortality from cardiovascular disease and type 2 diabetes.Diet plays an important role in the development of MetS.Studies have shown that edible dairy products are associated with blood lipids, blood pressure and cardiovascular diseases.In some short-term clinical trials, it has been found that long-term intake of dairy products can significantly reduce blood pressure. There is increasing evidence that dairy products (especially full-fat dairy products, fermented dairy products such as cheese or yogurt) may beBy affecting a variety of metabolic pathways, it has a positive effect on the body's basic metabolism.However, to date, most research on dairy products has been conducted in North America or Europe, and there have been very few studies on permanent residents from other regions (such as China, India, South America, and Africa).Different customs, dietary structure and economic income in different regions can have a huge impact on the research results.Recently, a prospective Urban Rural Epidemiology (PURE) study published in "BMJ Open Diabetes Research & Care", "Association of dairy consumption with metabolic syndrome, hypertension and diabetes in 147? 812 individuals from 21countries ”followed 147-812 study subjects from 21 countries (Argentina, Bangladesh, Brazil, Canada, Chile, China, Colombia, India, Iran, Malaysia, etc.) for many years to evaluate dairy product intake and MetSCorrelation of prevalence (cross-sectional analysis).The study found that higher intake of full-fat (rather than low-fat) dairy products is associated with a lower prevalence of MetS and most of its constituent factors, as well as a lower incidence of hypertension and diabetes [2].Research Methods The PURE study was a prospective epidemiological study of 35-year-old and 70-year-old individuals from 21 countries on five continents, with a median follow-up time of 9.1 years.In this cross-sectional analysis, the researchers evaluated the relationship between the intake of dairy products and the changes in MetS and its Xie characteristics through the analysis of five metabolic characteristics changes in MetS (n = 112922).Through this prospective analysis, the researchers also examined the correlation between dairy products and sudden hypertension (57,547 people without hypertension) and diabetes (131,481 people without diabetes).Findings: Dairy intake and prevalence of metabolic syndrome Researchers found that higher dairy intake (at least two servings per day) was associated with lower average systolic and diastolic blood pressure, waist circumference, body mass index, andTriglycerides are related to the ratio of HDL-C and blood glucose (covariates adjusted).The researchers also stated that there was no significant association between dairy product intake and other cardiovascular risk markers other than HDL-C.At the same time, the study also showed that only full-fat dairy products are associated with a lower prevalence of most MetS-related metabolic changes (including increased blood pressure, increased waist circumference, increased triglycerides and increased blood sugar), whileThe intake of low-fat dairy products has nothing to do with the prevalence of MetS.Findings: Dairy product intake and risk of developing hypertension and diabetes. Among the 57547 individuals who did not have hypertension at baseline, they found that a total of 13,640 (23.7%) people had hypertension during follow-up.Among 131,481 people without diabetes, 5351 (4.1%) were diagnosed with diabetes.Correlation analysis found that higher dairy product intake (at least two servings per day) was associated with a lower incidence of hypertension (HR 0.89, 95% CI 0.82-0.97, P = 0.02).For diabetes, a higher intake of dairy products (at least two servings per day) is associated with a lower incidence of diabetes (HR 0.88, 95% CI 0.76-1.02, P = 0.01).(Note that dairy products here refer to full-fat dairy products and not low-fat.) When the researchers evaluated the adjusted intake of full-fat dairy products and low-fat dairy products, they found that higher full-fat dairy productsIntake is significantly associated with the incidence of hypertension and diabetes.In contrast, there is no significant correlation between low-fat dairy products and hypertension or diabetes.In this study, through a prospective analysis of 147? 812 subjects in 21 countries (Argentina, Bangladesh, Brazil, Canada, Chile, China, Colombia, India, Iran, Malaysia, etc.), a more comprehensive analysis evaluatedHigh dairy intake is associated with the risk of metabolic syndrome (MetS), diabetes and hypertension.At the same time, it was found that higher intake of full-fat (rather than low-fat) dairy products is related to the lower prevalence of MetS and most of its constituent factors, and the lower incidence of hypertension and diabetes.This discovery has guiding significance for the future prevention and regulation of MetS, diabetes and hypertension.At the same time, the researchers suggest that the research results are confirmed in long-term trials large enough, so increasing dairy consumption may be a viable low-cost method that can reduce the prevalence of metabolic syndrome, hypertension, and diabetes, andEventually reduce cardiovascular events worldwide.references:. 1. Alberti, KGMM; Eckel Robert, H .; Grundy Scott, M ​​.; Zimmet Paul, Z .; Cleeman James, I .; Donato Karen, A .; Fruchart, J.-C .; James, WPT; Loria Catherine, M .; Smith Sidney, C. Harmonizing the Metabolic Syndrome. Circulation 2009, 120, 1640-1645, doi: 10.1161 / CIRCULATIONAHA.109.192644. 2. Bhavadharini, B .; Dehghan, M .; Mente, A .; Rangarajan,S .; Sheridan, P .; Mohan, V .; Iqbal, R .; Gupta, R .; Lear, S .; Wentzel-Viljoen, E., et al. Association of dairy consumption with metabolic syndrome, hypertension and diabetes in147? 812 individuals from 21 countries. BMJ Open Diabetes Research & Care 2020, 8, e000826, doi: 10.1136 / bmjdrc-2019-000826. The above content is only authorized for exclusive use by 39Health.com, please do not reprint without the authorization of the copyright party.

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DIABETES

What is the danger of diabetes?

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Maybe some people often have a question, if diabetes is just a little higher blood sugar, what’s the impact?In fact, high blood sugar affects the health of all aspects of our body. If it is not controlled well, it will cause many complications!1. Diabetic foot This is one of the more common complications of diabetic patients. Patients will have peripheral nerve and microvascular lesions, and the patient’s pain nerves will be damaged as a result.In this way, the sensitivity of the patient’s feet to external stimuli and injuries will be much reduced, and even some feet will be unconscious directly, and it is easy to get burned by heating in winter.2. Hypoglycemia usually occurs when the dose of hypoglycemic drugs in diabetes patients is too large, or the mismatch between medication and meal time results in hypoglycemia. If this phenomenon is not treated in time, serious consequences will occur.When there is hypoglycemia, dizziness, heart palpitations, and tremors will appear, and some will even be comatose because of hypoglycemia, which is very dangerous.3. Diabetic nephropathy, also known as glomerulosclerosis, is a very common complication that occurs in patients with diabetes.And this complication is difficult to treat. It is a microvascular complication that can cause kidney damage in patients.Urine protein, pyelonephritis, etc., which continue to develop will threaten the life of the patient.4. Nonketotic hyperosmolar coma This generally occurs in elderly diabetic patients, and nonketotic hyperosmolar coma will occur.The fatality rate of this complication is very high, patients will have severe hyperglycemia, dehydration and elevated plasma osmotic pressure, and some will be accompanied by coma symptoms.5. This complication of respiratory tract infection is more common in autumn and winter because of the temperature drop and the change of seasons.The chance of respiratory infection is very high, and the resistance of diabetic patients is much worse than normal people.Therefore, the chance of respiratory tract infection will also be relatively high, especially for some elderly patients.Diabetes is accompanied by other diseases. Once there is a respiratory infection, it will have a major impact on the body.6. The risk of atherosclerosis in patients with cardiovascular disease and diabetes is much higher than that in normal people. It appears in patients with type 2 diabetes.The main causes are coronary heart disease and cardiomyopathy, and patients will suffer from panic attacks and chest pain.7. Diabetic patients with cerebral thrombosis is a disease with high blood sugar, so the probability of thrombosis will be much higher than normal people.After the blood sugar is increased, the blood will become thicker, and the aggregation of platelets will increase a lot, so that the speed of blood flow will be slowed down, and cerebral thrombosis is easy to occur.When complications occur in diabetes, diabetes control is not ideal.Each complication is very serious and will endanger the safety of the patient. After suffering from diabetes, it is necessary to actively treat and prevent the occurrence of complications.

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DIABETES

Nature’s latest research | How obesity affects insulin and causes diabetes

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There is increasing evidence that the human intestinal flora plays a role in the development of obesity and related metabolic diseases.However, there are few studies to prove whether tissue-specific insulin sensitivity is related to specific microbial patterns.To this end, Nature recently published a study: “Individual and cohort-specific gut microbiota patterns associated with tissue-specific insulin sensitivity in overweight and obese males”.The study examined the insulin sensitivity of liver and peripheral adipose tissue and found a significant association between microbiota and tissue-specific insulin sensitivity, as well as the relative dynamics of the microbiota during obesity.The study divided the subjects into two cohorts, MAA and AMS. The subjects were all insulin resistant.The fasting blood glucose concentration was higher in the MAA group (6.1 ± 0.01 vs. 5.8 ± 0.09 mmol / l, p <0.05), while insulin was lower (16.8 ± 0.8 vs. 20.0 ± 1.2 mU / l, p <0.05).The β-cell function homeostasis model evaluation in the MAA group was lower than that in the AMS group. In the MAA group, 2 subjects lacked glycated hemoglobin.1. The composition of fecal flora found that the average flora of the two groups showed significant differences.Although Actinomycetes (Bifidobacterium and Propionibacterium) are more abundant in the MAA group, the genera of Clostridium clusters IV and XIVa are more abundant in the AMS group.In addition, uncultivated Clostridia I and II are more abundant in AMS.The study found that although most of the subjects in the MAA group had overlapping microbiome composition with the AMS group.However, it is worth noting that the first major component of the 1/3 MAA group is different, which explains the significant difference in the average flora composition between the two cohorts, indicating that some patients with metabolic syndrome from the MAA group have anotherA state of microbial composition.Analysis of fecal microbiota composition of 85 overweight men in MAA group and AMS group 2. Tissue-specific insulin sensitivity study After multiple tests and corrections, the insulin sensitivity of peripheral, liver, and adipose tissues did not show abundance of bacterial groupsRelated.However, after adjusting for age, body mass index (BMI), and waist-to-hip ratio, several taxa in both groups of subjects did significantly correlate with the percentage of Rd and EGP inhibition (Figure 3).Overall, the number of important associations and important taxa in MAA is higher.Moreover, in the two groups, the overall pattern of the correlation between specific taxa and tissue-specific insulin sensitivity was significantly different.3. Other measurements of glucose homeostasis and insulin sensitivity in the MAA group HbA1c (ρ0.57, p = 5.52E-05, q = 0.06), the abundance of specific microbiome groups and HOMA-IR, HOMA-B and fastingThere was no significant correlation between blood glucose.However, after adjusting for age, BMI, or waist-to-hip ratio, several taxa of the microflora did indeed correlate significantly with other measures of glucose homeostasis.Discussion The purpose of the study was to determine the relationship between microbial resistance levels, microbiome composition and tissue-specific insulin sensitivity in two independent obese male populations.The study evaluated the insulin sensitivity of peripheral, liver, and adipose tissue using a combination of high insulin and normal blood glucose, and found some associations between the microbial taxa and the insulin sensitivity of adipose tissue, liver, or skeletal muscle.This may indicate that when the body has developed an obese state, the role of the host microbiome can be predicted based on the baseline composition data.The above content is only authorized for exclusive use by 39Health.com, please do not reprint without the authorization of the copyright party.

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