close
CARDIOLOGY

All the concerns you have to eat eggs, let me clear it all at once!

no thumb

I love dead eggs. Even scorpions, moon cakes, and even ice creams eat egg yolks. Eggs are not only delicious, but also nutritious, making them the perfect food for humans. Of course, if the cholesterol content is not that high. When it comes to cholesterol, the egg is always the first to be beaten out. An egg contains about 186 mg of cholesterol, which is eaten two times a day. The cholesterol intake exceeds 300 mg, which makes people discouraged and hopes that the “egg” will sigh. However, the results of several recent studies on egg or dietary cholesterol and cardiovascular disease are not consistent. There are bad news. For example, in the “JAMA” in March this year, a study of nearly 30,000 people in the United States followed the 17-year study. The results showed that every time you eat half an egg, the risk of death increases by 8% in a step-by-step manner! A piece of glory! The new good news is that in May this year, a Finnish study found that eating one egg a day does not increase the risk of stroke. Last year, a study of over 500,000 people in China also showed that the risk of cardiovascular death was reduced by 18% per day for one egg! This is very confusing. I dare to say that this is a “Schrödinger’s egg.” Before you eat it, you don’t know whether it is life-saving or fatal. In the spirit of exploring and seeking knowledge, the mourners rushed into the waves on the Internet and felt a lot of emotions. Eggs are really not a “killer” without a story. Is “cholesterol harmful theory” a conspiracy? From a farce, the concept of “high cholesterol = cardiovascular disease” has long been popular. However, the 2017 edition of the US Dietary Guidelines has removed restrictions on cholesterol intake, and previous guidelines suggest that daily cholesterol intake should be less than 300 mg. Many people interpret it as “no matter how much cholesterol is ingested, it is harmless.” This has caused widespread public criticism of the “cholesterol harmful theory”, and there have been many voices that “rehabilitate” cholesterol. The disaster is not alone. Last September, an article entitled “Low-density lipoprotein cholesterol (LDL-C) does not cause cardiovascular disease: a comprehensive review of the current literature” was published in the “ExpertReview of Clinical Pharmacology” magazine, which is considered high. Insufficient evidence of cholesterol-induced cardiovascular disease has ignited widespread discussion among experts and the media about the harmful effects of cholesterol, and the authors of this review include top scientists in the cardiovascular field in several countries. Dr. Michel de Lorgeril, a French cardiologist who is one of the authors, even participated in the filming of a documentary entitled “Cholesterol Cheats”, revealing the huge chain of interests that may exist behind “cholesterolism” and suggesting a role for statins. Research data may lack rigor. Ever since, an article entitled “The mistakes of 40 years have finally been corrected: cholesterol is good and harmless, no longer good or bad…” began to burst in China. Cholesterol seems to be no longer the culprit of cardiovascular disease, but has become a “friend” of everyone. The statin has become harmful and has become synonymous with the chain of medical interests. But, is this the truth? With the event fermenting, in February of this year, the world’s 21 top cardiovascular journals published a joint front page, condemning the Internet and social media for spreading the wrong medical information, exaggerating the risk of statins, which may make patients who should be treated. Resistant to statins, exposed to cardiovascular disease risk. – “Mrs. Jones, according to your risk factors for heart attack, I suggest you start taking statins.” – “No, thank you, doctor, I saw too many terrible things about the drugs on the Internet. In addition, I am worried that some people in your profession will make these suggestions for personal economic interests. This is what I saw on the Internet.” The above dialogue is from a joint statement. It seems that the doctors in the United States are very troubled~ Otherwise, they will not force 21 top-level journals to come forward, and the front page will be condemned. Now let’s slowly analyze the beginning and end of this farce. The new edition of the American Dietary Guidelines has eliminated the upper limit of cholesterol intake, in fact, because of dietary cholesterol intake and elevated serum cholesterol. This involves the next issue that needs to be discussed, which is briefly taken here.On the other hand, the revision of the guideline may be based on the fact that the evidence-based evidence of the specific value of 300 mg is insufficient, so remove the restriction first. genius! Let me talk about the “God”. The “Expert Review of Clinical Pharmacology” magazine can only be ranked in the 3 districts in the medical journals. In terms of the content of the article, there is a very serious phenomenon that the unscrupulous media is partial and complete. In academic research, there is a dispute that is normal. We know very little about cardiovascular disease, and the cholesterol theory does face many challenges. On the one hand, the theory of cholesterol does not explain all coronary heart disease. The mechanism of atherosclerosis induced by LDL-C is not fully understood. Even LDL-C may not be the best indicator of the relationship between cholesterol theory and atherosclerosis. . “God” mentioned that, based on many shortcomings in previous research, the correct statement is that high cholesterol and LDL-C predict the occurrence of cardiovascular disease in the future, but the correlation and causality are two different concepts. In the future, it may be possible to make up for these shortcomings through more rigorous research designs. The purpose of the researcher’s publication is to allow everyone to broaden their horizons, think and explore perhaps better ways to lower cholesterol and prevent atherosclerosis and cardiovascular disease. The relationship between cholesterol and atherosclerosis is not as sloppy as some media have said, but has gone through a long scientific process from pathology, animal experiments, epidemiology to large-scale clinical intervention trials. Statins, like any other drug, have side effects, but side effects are not worth mentioning. Even US President Trump is eating a statin. What are you afraid of? The most common thing for bad media is to intercept a certain flawed node and conduct a full-scale attack. The “reconciliation” of this cholesterol, at present, seems to be a farce. Eat more eggs, cholesterol will be higher? ——The impact is affirmative, but specifically the individual said some controversy about “cholesterol harmful theory”, and then talk about the relationship between dietary cholesterol and serum cholesterol. The more cholesterol you eat, the higher your serum cholesterol? The amount of liver cholesterol synthesis in adults is about 1000~2000 mg per day. The body can maintain the relative stability of serum cholesterol through a regulatory mechanism. The more cholesterol is ingested, the less synthetic cholesterol is. However, this regulatory mechanism is limited, so dietary cholesterol still has an effect on serum cholesterol. And this effect lacks general rules, is not a simple linear relationship, and even specific to everyone. The academic community divides the reaction of blood cholesterol after eating eggs into “high-reactivity type” and “low-reaction type”. However, a person can be highly reactive at certain times and low-reactive at certain times. (How is this still played?) In many experiments that studied eating 1-2 eggs a day, no egg was found to have a significant effect on blood cholesterol. Studies have shown that after 14 days of eating up to 8 eggs (1500 mg of cholesterol), blood cholesterol changes from 6 mg/dL to 75 mg/dL. An epidemiological survey of 27,378 people in the United States between 1988 and 1994 found that overall, there was no significant relationship between the number of eggs eaten and serum cholesterol levels. This is probably one of the reasons why the US Dietary Guidelines have lifted restrictions on cholesterol intake. If you still have to ask: “When you eat more eggs, is the cholesterol high?” Then I can only answer: “No comment!” Does eating eggs cause an increased risk of cardiovascular disease? Still no comment! Since there is no way to make it clear that the specific effect of eating eggs on serum cholesterol, then directly analyze the relationship between eating eggs and cardiovascular disease risk, right? However, it must be emphasized that studies on egg intake and cardiovascular disease risk are basically unable to accurately estimate the actual number of eggs eaten. It is generally based on memories to estimate the egg intake in the past 1 year or even years. Who can stand it? Originally, eating eggs is because of poor memory and supplementing the brain. You remind me to eat a few eggs last year, I will give you a rough number, oh, then you will give me a rough study. No need, this is really unnecessary.Such a study, even if the accuracy is sufficient, can only lead to a conclusion of relevance and cannot prove causality. Let’s take a look at the study released in the United States in March this year. The authors have integrated the data from six completely different studies. Isn’t this making the bias even greater? The conclusion of the study is that the risk increases by 6%, and the relative risk is increased. The risk of death from ordinary people is not high. The multiplication of 0 by 1000% is still 0, not to mention 106%. Other similar studies have not found that egg intake increases the risk of cardiovascular disease. So, can eggs eat more? If you see this, you still have a question mark: “Well? So I should eat a few eggs? How do I feel like you have said everything, and I don’t seem to say anything?” For this situation, it is recommended to eat more. It may be helpful to supplement the nutrition of several eggs. Eggs are a kind of food with risks and benefits. The risk is still not clear, but can’t you say that there is no risk? Considering the benefits and possible risks, and then analyzing the different situations of different individuals, it may be a good choice to develop an individualized “eaten plan”. Overall, the day a egg, very good, very satisfied ~ This article first appeared: the medical profession cardiovascular Channel author: Lethe.
This article typesetting: Forgetting the responsibility Editor: Xiao Xiaohui , please do not reprint without the authorization of the copyright party.

ouyangshaoxia

The author ouyangshaoxia